soft-matter bio-barriers, engineered for everyday life

From dual-polymer nasal sprays to next-generation mucosal and anti-fibrotic platforms, our work turns advanced biomaterials into practical medical devices.

Explore the Science

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See It In Action

soft-matter bio-barriers, engineered for everyday life

From dual-polymer nasal sprays to next-generation mucosal and anti-fibrotic platforms, our work turns advanced biomaterials into practical medical devices.

Explore the Science

Shop Now

See It In Action
Alt image

lab results behind norizite® nasal spray

Laboratory experiments on human and mink lung epithelial cells demonstrate that NoriZite® Nasal Spray completely blocks infection from all primary isolated viral variants tested.

Core innovation: Structured Bio-engineering

Many sprays use similar raw materials. The difference is structure. At higher concentrations, conventional formulations can become thick and spray as a narrow jet. That reduces coverage and comfort. NoriZite® is engineered so it does three things together: sprays as a fine mist, forms a coherent barrier layer on contact, and stays in place for longer.

Plume-to-Gel transition

When sprayed, the formulation shear-thins and atomises into a cloud of droplets. After landing on the moist lining, it rapidly recovers into a soft, elastic fluid-gel layer that forms a more continuous coating than isolated droplets.

The Plume-to-Gel Transition

Witness the unique rheological transformation from fine mist spray to high-retention protective gel in milliseconds.

Spray pattern imaging

gellan vs λ-carrageenan

Title

0.2% (low), 0.4% (medium), 1.0% (high). Gellan maintains a round cloud mist across concentrations. λ-carrageenan deforms at 0.4% and becomes a narrow jet at 1.0%. 

Rheology

shear-thinning + recovery

Title

Viscosity drops under shear so the spray can atomise into a mist. After spraying, the material recovers (dynamic yielding) and resists running, which helps the layer stay in place after application.

The Plume-to-Gel Transition

Witness the unique rheological transformation from fine mist spray to high-retention protective gel in milliseconds.

Spray pattern imaging

gellan vs λ-carrageenan

Title

0.2% (low), 0.4% (medium), 1.0% (high). Gellan maintains a round cloud mist across concentrations. λ-carrageenan deforms at 0.4% and becomes a narrow jet at 1.0%. 

Rheology

shear-thinning + recovery

Title

Viscosity drops under shear so the spray can atomise into a mist. After spraying, the material recovers (dynamic yielding) and resists running, which helps the layer stay in place after application.

the three engineering dimensions

1

Barrier

Title

Mechanism: non-pharmacological physical barrier formation. 

It does not claim to kill pathogens. It reduces contact and diffusion opportunity through structure.

2

Coverage

Title

Challenge: higher concentration often causes jetting and reduces coverage. Solution: shear-thinning design keeps a stable mist pattern at higher protective concentrations.

3

Retention

Title

Challenge: mucociliary clearance removes most liquid sprays quickly. Solution: the dual-polymer matrix is designed to resist clearance and remain detectable for longer in controlled studies.

Beyond the Nose: Soft-Matter Platforms in Development

The same soft-matter design principles are being applied to other mucosal and tissue environments in our research and development programs.

Exploratory

Ocular surface comfort concepts

Spray concepts designed for long-lasting hydration and comfort on the ocular surface.

Formulation Validated

Intimate care gels

RiNOZiTE® Vaginal Gel, Adjacent soft-matter mucosal comfort systems for intimate care.

In Development

Soft-matter wound and scar-care barrier concepts

Conformal gellan membranes and barrier spray concepts for wound coverage, hydration and scar-modulation pathways.

Some applications are still in development and are not commercially available. For additional technical information on the broader platform, visit Birmingham Biomat.