structured bio-barrier science for everyday nasal protection

NoriZite® combines sprayability, coverage and mucoadhesion in a dual-polymer system designed to form a soft physical barrier layer in the nose.

Explore the Science

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See It In Action

structured bio-barrier science for everyday nasal protection

NoriZite® combines sprayability, coverage and mucoadhesion in a dual-polymer system designed to form a soft physical barrier layer in the nose.

Explore the Science

Shop Now

See It In Action
Alt image

how the spray plume transitions into a coherent gel-like barrier layer 

Laboratory and transwell studies support NoriZite®’s physical-barrier mechanism, showing reduced permeation and reduced viral diffusion under specific experimental conditions.
These findings are based on laboratory test systems and do not guarantee real-world performance.

*These findings are based on laboratory test systems and do not guarantee real-world performance.

Core innovation: Structured Bio-engineering

Many sprays use similar raw materials. The difference is structure. NoriZite® is engineered to do three things together: spray as a broader mist, form a coherent barrier layer on contact, and stay in place for longer.

Plume-to-Gel transition

When sprayed, the formulation shear-thins and atomises into a cloud of droplets. After landing on the moist lining, it rapidly recovers into a soft gel-like barrier layer that forms a more continuous coating than isolated droplets.

The Plume-to-Gel Transition

Witness the unique rheological transformation from fine mist spray to high-retention protective gel in milliseconds.

Spray pattern imaging

gellan vs λ-carrageenan

Title

0.2% (low), 0.4% (medium), 1.0% (high). Gellan maintains a round cloud mist across concentrations. λ-carrageenan deforms at 0.4% and becomes a narrow jet at 1.0%. 

Rheology

shear-thinning + recovery

Title

Viscosity drops under shear so the spray can atomise into a mist. After spraying, the material recovers (dynamic yielding) and resists running, which helps the layer stay in place after application.

The Plume-to-Gel Transition

Witness the unique rheological transformation from fine mist spray to high-retention protective gel in milliseconds.

Spray pattern imaging

Broader plume, better surface coverage

Title

At tested concentrations, gellan-containing systems maintained a broader, rounder mist pattern than carrageenan alone.

Rheology

Sprays easily. Recovers quickly.

Title

Shear-thinning supports atomisation during spraying. Recovery after spraying helps the barrier layer resist running and remain in place for longer.

the three engineering dimensions

1

Barrier

Title

Non-pharmacological physical barrier formation.

2

Coverage

Title

Formulation design that supports broad mist formation rather than narrow jetting.

3

Retention

Title

A dual-polymer matrix designed to remain detectable for longer in controlled studies.

Beyond the Nose: Soft-Matter Platforms in Development

The same soft-matter design principles are being explored for other mucosal and tissue environments within the broader platform.

Exploratory

Ocular surface comfort concepts

Spray concepts designed for long-lasting hydration and comfort on the ocular surface.

Formulation Validated

Intimate care gels

RiNOZiTE® Vaginal Gel, Adjacent soft-matter mucosal comfort systems for intimate care.

In Development

Soft-matter wound and scar-care barrier concepts

Conformal gellan membranes and barrier spray concepts for wound coverage, hydration and scar-modulation pathways.

Some applications are still in development and are not commercially available. For additional technical information on the broader platform, visit Birmingham Biomat. 

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FAQs

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FAQs